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Friday, March 13, 2015

Isoproscaline or 4-(i)-propoxy-3,5-dimethoxyphenethylamine is an analogue of mescaline. It is closely related to proscaline and was first synthesized by David E. Nichols. It produces hallucinogenic, psychedelic, and entheogenic effects.

Chemistry



Isoproscaline is in a class of compounds commonly known as phenethylamines, and the full chemical name is 2-(4-isopropoxy-3,5-dimethoxyphenyl)ethanamine.

Effects



Little is known about the psychopharmacological effects of isoproscaline. Alexander Shulgin lists a psychedelic dosage as being 40â€"80 mg, with effects lasting 12â€"18 hours.

Pharmacology



The mechanism that produces the hallucinogenic and entheogenic effects of isoproscaline is most likely to result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines.

Dangers



The toxicity of isoproscaline is not known.

Legality



Isoproscaline is unscheduled and unregulated in the United States, however because of its close similarity in structure and effects to mescaline, possession and sale of isoproscaline may be subject to prosecution under the Federal Analog Act.

In the UK its highly likely that this compound would be covered by the "phenylethylamine amendment" to the misuse of drugs act likely rendering it (probably) a Class A controlled drug.

See also



  • Proscaline
  • PiHKAL

External links



  • Isoproscaline entry in PiHKAL
  • Isoproscaline entry in PiHKAL • info


 
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