This is a list of adrenergic drugs. These are pharmaceutical drugs, naturally occurring compounds and other chemicals that influence the function of the neurotransmitter epinephrine (adrenaline).
§Receptor ligands
§α1-adrenergic receptor ligands
§Agonists
§Antagonists
Many tricyclic antidepressants, tetracyclic antidepressants, antipsychotics, ergolines, and some piperazines like buspirone, trazodone, nefazodone, etoperidone, and mepiprazole antagonize α1-adrenergic receptors as well, which contributes to their side effects such as orthostatic hypotension.
§α2-adrenergic receptor ligands
§Agonists
§Antagonists
Many atypical antipsychotics and azapirones like buspirone and gepirone (via metabolite pyrimidinylpiperazine) antagonize α2-adrenergic receptors as well.
§β-adrenergic receptor ligands
§Agonists
§Antagonists
§Reuptake inhibitors
§Norepinephrine transporter (NET) inhibitors
§Vesicular monoamine transporter (VMAT) inhibitors
§Releasing agents
§Enzyme inhibitors
§Anabolism
§Phenylalanine hydroxylase (PAH) inhibitors
§Tyrosine hydroxylase inhibitors
§Aromatic L-amino acid decarboxylase (AAAD) inhibitors
§Dopamine-beta-hydroxylase (DBH) inhibitors
§Phenylethanolamine N-methyltransferase (PNMT) inhibitors
§Catabolism
§Monoamine oxidase (MAO) inhibitors
MAO-B inhibitors also influence norepinephrine/epinephrine levels since they inhibit the breakdown of their precursor dopamine.